PHARMACEUTICAL FORM AND COMPOSITION
In 1 ml of the injection solution contains 50 mg of carprofen as an active substance and a preservative – 1% benzyl alcohol. In appearance it is a transparent solution of light yellow color. It is produced in 20 ml bottles of dark glass, which are packed in cardboard boxes.
Rimadil belongs to the group of non-steroidal anti-inflammatory drugs. It has anti-inflammatory, analgesic and vetprofen desage antipyretic effects. Carprofen, the active substance of rimadil, in a cycle of arachidonic acid mainly inhibits cycloxygenase II, which is produced in the body in response to inflammation. This inhibits the synthesis of inflammatory prostaglandins that cause inflammation, swelling and pain. In therapeutic doses, carprofen has a much weaker effect on cycloxygenase I, and thus has no effect on the synthesis of protective prostaglandins. Carprofen does not prevent normal physiological processes in tissues. Carprofen binds to plasma proteins by more than 99%. The drug is metabolized in the Dmitry Sazonov liver, excreted with faeces (about 80%), as well as urine.
Assigned only to dogs to relieve inflammation and pain in acute and chronic diseases of the musculoskeletal system (osteoarthritis), for analgesia and as an anti-inflammatory agent to reduce postoperative pain and swelling.
DOSES AND METHODS OF USE
The preparation is administered intravenously or subcutaneously at the rate of 4 mg per 1 kg of animal weight, which corresponds to 1 ml of solution per 12.5 kg of animal weight. If necessary, rimadil 5% solution for injection is repeated not earlier than 24 hours in half dose: 2 mg per 1 kg of animal weight, which corresponds to 1 ml solution per 25 kg of animal weight. It is recommended to administer the drug during premedication or during anesthesia. In case of further therapy, the treatment may be continued by prescribing rimadil in the form of tablets. The duration of therapy depends on the condition of the animal, but after 14 days of treatment the animal must be examined again by a veterinarian.
Allergic reactions are possible in hypersensitive animals. Vomiting may occur in rare cases.
Hypersensitivity to the drug. Do not administer rimadil 5% solution for intramuscular injection. Do not use puppy bitches. The drug should be administered with caution to https://pillintrip.com/medicine/vetprofen-dogs animals with heart, kidney and liver diseases. It is not recommended to administer other non-steroidal anti-inflammatory drugs or nephrotoxic drugs earlier than 24 hours after administration of rimadil.
Do not exceed the prescribed dose Dmitry Sazonov or treatment duration. If carprofen and warfarin are used at the same time, the clinical situation must be carefully monitored, as both drugs bind to plasma proteins.